There is a difference in the type of bones and the nutritional content of the resulting broth. Soup bones are typically larger cuts of bones that have been trimmed of meat and may include a mixture of different types of bones, such as beef shanks or short ribs. Marrow bones, on the other hand, are typically cut from the center of long bones, such as the femur or the humerus, and are rich in marrow. The broth made from marrow bones will be richer and more flavorful than that made from soup bones, and will also contain more fat and nutrients, such as collagen, glycine, and minerals.